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» Question-answering by predictive annotation
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ISMB
2004
15 years 5 months ago
Exploiting conserved structure for faster annotation of non-coding RNAs without loss of accuracy
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
Zasha Weinberg, Walter L. Ruzzo
BMCBI
2008
75views more  BMCBI 2008»
15 years 4 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...
ISMB
1993
15 years 5 months ago
Transmembrane Segment Prediction from Protein Sequence Data
Weconsider tile automatedidentification of transmembrane domains in membrane protein sequences. 324 proteins (containing 1585 segrrmnts) werc examined, representing every protein ...
Sholom M. Weiss, Dawn M. Cohen, Nitin Indurkhya
GCB
2010
Springer
198views Biometrics» more  GCB 2010»
15 years 2 months ago
RNALfoldz: Efficient Prediction of Thermodynamically Stable, Local Secondary Structures
Abstract: The search for local RNA secondary structures and the annotation of unusually stable folding regions in genomic sequences are two well motivated bioinformatic problems. I...
Andreas R. Gruber, Stephan H. F. Bernhart, You Zho...
SDM
2009
SIAM
105views Data Mining» more  SDM 2009»
16 years 1 months ago
Exploiting Semantic Constraints for Estimating Supersenses with CRFs.
The annotation of words and phrases by ontology concepts is extremely helpful for semantic interpretation. However many ontologies, e.g. WordNet, are too fine-grained and even hu...
Gerhard Paaß, Frank Reichartz