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BIOINFORMATICS
2005
58views more  BIOINFORMATICS 2005»
13 years 10 months ago
RDP2: recombination detection and analysis from sequence alignments
Darren P. Martin, C. Williamson, David Posada
GCB
2000
Springer
137views Biometrics» more  GCB 2000»
14 years 2 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
BMCBI
2006
92views more  BMCBI 2006»
13 years 11 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
CSB
2004
IEEE
141views Bioinformatics» more  CSB 2004»
14 years 2 months ago
MinPD: Distance-Based Phylogenetic Analysis and Recombination Detection of Serially-Sampled HIV Quasispecies
A new computational method to study within-host viral evolution is explored to better understand the evolution and pathogenesis of viruses. Traditional phylogenetic tree methods a...
Patricia Buendia, Giri Narasimhan
JCB
2002
116views more  JCB 2002»
13 years 10 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye