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BMCBI
2011
13 years 2 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
BMCBI
2010
198views more  BMCBI 2010»
13 years 7 months ago
ClustalXeed: a GUI-based grid computation version for high performance and terabyte size multiple sequence alignment
Background: There is an increasing demand to assemble and align large-scale biological sequence data sets. The commonly used multiple sequence alignment programs are still limited...
Taeho Kim, Hyun Joo
RECOMB
2002
Springer
14 years 7 months ago
Revealing protein structures: a new method for mapping antibody epitopes
A recent idea for determining the three-dimensional structure of a protein uses antibody recognition of surface structure and random peptide libraries to map antibody epitope comb...
Brendan Mumey, Brian W. Bailey, Edward A. Dratz
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
14 years 25 days ago
Prokaryote Phylogeny without Sequence Alignment: From Avoidance Signature to Composition Distance
A new and essentially simple method to reconstruct prokaryotic phylogenetic trees from their complete genome data without using sequence alignment is proposed. It is based on the ...
Bailin Hao, Ji Qi
ICIP
2005
IEEE
14 years 1 months ago
Medical image registration based on random line sampling
One of the key aspects in 3D-image registration is the computation of the joint intensity histogram. We propose a new approach to compute this histogram using uniformly distribute...
Anton Bardera, Miquel Feixas, Imma Boada, Mateu Sb...