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BMCBI
2010
104views more  BMCBI 2010»
13 years 8 months ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang
BMCBI
2010
198views more  BMCBI 2010»
13 years 8 months ago
ClustalXeed: a GUI-based grid computation version for high performance and terabyte size multiple sequence alignment
Background: There is an increasing demand to assemble and align large-scale biological sequence data sets. The commonly used multiple sequence alignment programs are still limited...
Taeho Kim, Hyun Joo
CC
2008
Springer
133views System Software» more  CC 2008»
13 years 8 months ago
Hardness Amplification via Space-Efficient Direct Products
We prove a version of the derandomized Direct Product lemma for deterministic space-bounded algorithms. Suppose a Boolean function g : {0, 1}n {0, 1} cannot be computed on more th...
Venkatesan Guruswami, Valentine Kabanets
DAM
2010
112views more  DAM 2010»
13 years 8 months ago
New results on optimizing rooted triplets consistency
Abstract. A set of phylogenetic trees with overlapping leaf sets is consistent if it can be merged without conflicts into a supertree. In this paper, we study the polynomial-time a...
Jaroslaw Byrka, Sylvain Guillemot, Jesper Jansson
CANDC
2006
ACM
13 years 8 months ago
Dealing with repetitions in sequencing by hybridization
DNA sequencing by hybridization (SBH) induces errors in the biochemical experiment. Some of them are random and disappear when the experiment is repeated. Others are systematic, i...
Jacek Blazewicz, Fred Glover, Marta Kasprzak, Wojc...
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