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ICCSA
2004
Springer
14 years 2 months ago
High Throughput in-silico Screening against Flexible Protein Receptors
We report results for the in-silico screening of a database of 10000 flexible compounds against various crystal structures of the thymidine kinase receptor complexed with 10 know...
Holger Merlitz, Wolfgang Wenzel
HAIS
2009
Springer
14 years 1 months ago
Hybrid Evolutionary Algorithm for Solving Global Optimization Problems
Differential Evolution (DE) is a novel evolutionary approach capable of handling non-differentiable, non-linear and multi-modal objective functions. DE has been consistently ranked...
Radha Thangaraj, Millie Pant, Ajith Abraham, Youak...
HIM
1997
Springer
162views Multimedia» more  HIM 1997»
14 years 1 months ago
Probabilistic Logical Information Retrieval for Content, Hypertext, and Database Querying
Classical retrieval models support content-oriented searching for documents using a set of words as data model. However, in hypertext and database applications we want to consider...
Thomas Rölleke, Markus Blömer
TREC
2004
13 years 10 months ago
Can We Get A Better Retrieval Function From Machine?
The quality of an information retrieval system heavily depends on its retrieval function, which returns a similarity measurement between the query and each document in the collect...
Weiguo Fan, Wensi Xi, Edward A. Fox, Li Wang
BMCBI
2010
104views more  BMCBI 2010»
13 years 9 months ago
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative th
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...
Yunqi Li, C. Russell Middaugh, Jianwen Fang