We report results for the in-silico screening of a database of 10000 flexible compounds against various crystal structures of the thymidine kinase receptor complexed with 10 know...
Differential Evolution (DE) is a novel evolutionary approach capable of handling non-differentiable, non-linear and multi-modal objective functions. DE has been consistently ranked...
Classical retrieval models support content-oriented searching for documents using a set of words as data model. However, in hypertext and database applications we want to consider...
The quality of an information retrieval system heavily depends on its retrieval function, which returns a similarity measurement between the query and each document in the collect...
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...