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» Rapid detection of significant spatial clusters
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BMCBI
2005
109views more  BMCBI 2005»
13 years 7 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
GISCIENCE
2010
Springer
212views GIS» more  GISCIENCE 2010»
13 years 8 months ago
Qualitative Change to 3-Valued Regions
Regions which evolve over time are a significant aspect of many phenomena in geographic information science. Examples include areas in which a measured value (e.g. temperature, sal...
Matt Duckham, John G. Stell, Maria Vasardani, Mich...
BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2008
148views more  BMCBI 2008»
13 years 7 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...