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BMCBI
2011
13 years 3 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein
PAA
2007
13 years 8 months ago
Pairwise feature evaluation for constructing reduced representations
Feature selection methods are often used to determine a small set of informative features that guarantee good classification results. Such procedures usually consist of two compon...
Artsiom Harol, Carmen Lai, Elzbieta Pekalska, Robe...
GECCO
2010
Springer
237views Optimization» more  GECCO 2010»
14 years 1 months ago
Benchmarking the (1, 4)-CMA-ES with mirrored sampling and sequential selection on the noiseless BBOB-2010 testbed
The well-known Covariance Matrix Adaptation Evolution Strategy (CMA-ES) is a robust stochastic search algorithm for optimizing functions defined on a continuous search space RD ....
Anne Auger, Dimo Brockhoff, Nikolaus Hansen
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
BMCBI
2006
165views more  BMCBI 2006»
13 years 8 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...