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BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
BS Seeker: precise mapping for bisulfite sequencing
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
Pao-Yang Chen, Shawn Cokus, Matteo Pellegrini
BMCBI
2006
121views more  BMCBI 2006»
13 years 7 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
NAR
2006
134views more  NAR 2006»
13 years 7 months ago
The MPI Bioinformatics Toolkit for protein sequence analysis
The MPI Bioinformatics Toolkit is an interactive web service which offers access to a great variety of public and in-house bioinformatics tools. They are grouped into different se...
Andreas Biegert, Christian Mayer, Michael Remmert,...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
HPDC
2010
IEEE
13 years 8 months ago
MPIPairwiseStatSig: parallel pairwise statistical significance estimation of local sequence alignment
Sequence comparison is considered as a cornerstone application in bioinformatics, which forms the basis of many other applications. In particular, pairwise sequence alignment is a...
Ankit Agrawal, Sanchit Misra, Daniel Honbo, Alok N...