Physical map reconstruction in the presence of errors is a central problem in genetics of high computational complexity. A parallel genetic algorithm for a maximum likelihood esti...
Suchendra M. Bhandarkar, Jinling Huang, Jonathan A...
Background: A metabolic network is the sum of all chemical transformations or reactions in the cell, with the metabolites being interconnected by enzyme-catalyzed reactions. Many ...
Wei-chung Liu, Wen-hsien Lin, Andrew J. Davis, Fer...
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...