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BMCBI
2010
110views more  BMCBI 2010»
13 years 8 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
RECOMB
2002
Springer
14 years 9 months ago
DNA sequence evolution with neighbor-dependent mutation
We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this c...
Peter F. Arndt, Christopher B. Burge, Terence Hwa
CSC
2006
13 years 10 months ago
B-Splines for Genomic Signatures
- A variety of data analysis concerned with genome sequences support the proposal that each living organism owns a genomic signature. Classical approaches to the genomic signature ...
Gennaro Iaccarino, Filomena de Santis
BMCBI
2010
144views more  BMCBI 2010»
13 years 8 months ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...
JCB
2008
52views more  JCB 2008»
13 years 8 months ago
Spectrum-Based De Novo Repeat Detection in Genomic Sequences
A novel approach to the detection of genomic repeats is presented in this paper. The technique, dubbed SAGRI (Spectrum Assisted Genomic Repeat Identifier), is based on the spectru...
Huy Hoang Do, Kwok Pui Choi, Franco P. Preparata, ...