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» Reducibility and Completeness in Private Computations
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BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
204views more  BMCBI 2008»
13 years 7 months ago
EST2uni: an open, parallel tool for automated EST analysis and database creation, with a data mining web interface and microarra
Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
Javier Forment, Francisco Gilabert Villamón...
BMCBI
2008
136views more  BMCBI 2008»
13 years 7 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
BMCBI
2005
98views more  BMCBI 2005»
13 years 7 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
JMLR
2002
111views more  JMLR 2002»
13 years 7 months ago
The Learning-Curve Sampling Method Applied to Model-Based Clustering
We examine the learning-curve sampling method, an approach for applying machinelearning algorithms to large data sets. The approach is based on the observation that the computatio...
Christopher Meek, Bo Thiesson, David Heckerman