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BMCBI
2006
152views more  BMCBI 2006»
13 years 10 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2006
74views more  BMCBI 2006»
13 years 10 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane
BMCBI
2006
172views more  BMCBI 2006»
13 years 10 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BMCBI
2006
96views more  BMCBI 2006»
13 years 10 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
BMCBI
2006
150views more  BMCBI 2006»
13 years 10 months ago
Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
Alla Bulashevska, Roland Eils
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