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BMCBI
2008
178views more  BMCBI 2008»
15 years 6 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
201views more  BMCBI 2008»
15 years 6 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2008
136views more  BMCBI 2008»
15 years 6 months ago
GPAT: Retrieval of genomic annotation from large genomic position datasets
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Arnaud Krebs, Mattia Frontini, Làszlò...
BMCBI
2008
103views more  BMCBI 2008»
15 years 6 months ago
The VirusBanker database uses a Java program to allow flexible searching through Bunyaviridae sequences
Background: Viruses of the Bunyaviridae have segmented negative-stranded RNA genomes and several of them cause significant disease. Many partial sequences have been obtained from ...
Mathieu Fourment, Mark J. Gibbs
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
Principal components analysis based methodology to identify differentially expressed genes in time-course microarray data
Background: Time-course microarray experiments are being increasingly used to characterize dynamic biological processes. In these experiments, the goal is to identify genes differ...
Sudhakar Jonnalagadda, Rajagopalan Srinivasan
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