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» Representation for Discovery of Protein Motifs
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RECOMB
2008
Springer
14 years 8 months ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
DATAMINE
2007
135views more  DATAMINE 2007»
13 years 7 months ago
Experiencing SAX: a novel symbolic representation of time series
Many high level representations of time series have been proposed for data mining, including Fourier transforms, wavelets, eigenwaves, piecewise polynomial models etc. Many researc...
Jessica Lin, Eamonn J. Keogh, Li Wei, Stefano Lona...
ML
1998
ACM
115views Machine Learning» more  ML 1998»
13 years 7 months ago
Pharmacophore Discovery Using the Inductive Logic Programming System PROGOL
This paper is a case study of a machine aided knowledge discovery process within the general area of drug design. More speci cally, the paper describes a sequence of experiments in...
Paul W. Finn, Stephen Muggleton, David Page, Ashwi...
VLDB
2005
ACM
125views Database» more  VLDB 2005»
14 years 8 months ago
Sync your data: update propagation for heterogeneous protein databases
The traditional model of bench (wet) chemistry in many life sciences domain is today actively complimented by computer-based discoveries utilizing the growing number of online data...
Kajal T. Claypool, Elke A. Rundensteiner
CIKM
2006
Springer
13 years 11 months ago
Structure-based querying of proteins using wavelets
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
Keith Marsolo, Srinivasan Parthasarathy, Kotagiri ...