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» Representation for Discovery of Protein Motifs
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BMCBI
2011
12 years 11 months ago
Binding Site Prediction for Protein-Protein Interactions and Novel Motif Discovery using Re-occurring Polypeptide Sequences
Background: While there are many methods for predicting protein-protein interaction, very few can determine the specific site of interaction on each protein. Characterization of t...
Adam Amos-Binks, Catalin Patulea, Sylvain Pitre, A...
GCB
2000
Springer
99views Biometrics» more  GCB 2000»
13 years 11 months ago
Structure Motif Discovery and Mining the PDB
We describe an algorithm for the automatic discovery of recurring patterns in protein structures. The patterns consist of individual residues having a defined order along the prote...
Inge Jonassen, Ingvar Eidhammer, Darrell Conklin, ...
SAC
2009
ACM
14 years 2 months ago
A new protein motif extraction framework based on constrained co-clustering
Signal finding (pattern discovery) in biological sequences is a fundamental problem in both computer science and molecular biology. Many approaches have been proposed for extract...
Francesca Cordero, Alessia Visconti, Marco Botta
JCB
2000
71views more  JCB 2000»
13 years 7 months ago
Structure Comparison and Structure Patterns
This article investigates aspects of pairwise and multiple structure comparison, and the problem of automatically discover common patterns in a set of structures. Descriptions and...
Ingvar Eidhammer, Inge Jonassen, William R. Taylor
ALMOB
2006
138views more  ALMOB 2006»
13 years 7 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh