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JGO
2011
89views more  JGO 2011»
12 years 10 months ago
Model building using bi-level optimization
Abstract In many problems from different disciplines such as engineering, physics, medicine, and biology, a series of experimental data is used in order to generate a model that ca...
Georges K. Saharidis, Ioannis P. Androulakis, Mari...
BMCBI
2010
179views more  BMCBI 2010»
13 years 7 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2006
175views more  BMCBI 2006»
13 years 7 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
DEBU
2010
180views more  DEBU 2010»
13 years 7 months ago
Searching RDF Graphs with SPARQL and Keywords
The proliferation of knowledge-sharing communities like Wikipedia and the advances in automated information extraction from Web pages enable the construction of large knowledge ba...
Shady Elbassuoni, Maya Ramanath, Ralf Schenkel, Ge...
JCB
2002
160views more  JCB 2002»
13 years 7 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...