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ALMOB
2008
160views more  ALMOB 2008»
15 years 6 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
BIODATAMINING
2008
178views more  BIODATAMINING 2008»
15 years 6 months ago
Clustering-based approaches to SAGE data mining
Serial analysis of gene expression (SAGE) is one of the most powerful tools for global gene expression profiling. It has led to several biological discoveries and biomedical appli...
Haiying Wang, Huiru Zheng, Francisco Azuaje
BIOINFORMATICS
2007
102views more  BIOINFORMATICS 2007»
15 years 6 months ago
OmicBrowse: a browser of multidimensional omics annotations
OmicBrowse is a browser to explore multiple datasets coordinated in the multidimensional omic space integrating omics knowledge ranging from genomes to phenomes and connecting evo...
Tetsuro Toyoda, Yoshiki Mochizuki, Keith Player, N...
BMCBI
2010
86views more  BMCBI 2010»
15 years 6 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2010
176views more  BMCBI 2010»
15 years 6 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...