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BMCBI
2008
13 years 11 months ago
2008
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
BMCBI
2008
13 years 11 months ago
2008
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
BMCBI
2008
13 years 11 months ago
2008
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
BMCBI
2008
13 years 11 months ago
2008
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
BMCBI
2008
13 years 11 months ago
2008
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...