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BMCBI
2010
145views more  BMCBI 2010»
13 years 4 months ago
Directionality in protein fold prediction
Background: Ever since the ground-breaking work of Anfinsen et al. in which a denatured protein was found to refold to its native state, it has been frequently stated by the prote...
Jonathan J. Ellis, Fabien P. E. Huard, Charlotte M...
BMCBI
2010
172views more  BMCBI 2010»
13 years 4 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
ASC
2011
13 years 4 months ago
Autonomic fault-handling and refurbishment using throughput-driven assessment
A new paradigm for online EH regeneration using Genetic Algorithms (GAs) called Competitive Runtime Reconfiguration (CRR) is developed where performance is assessed based upon a b...
Ronald F. DeMara, Kening Zhang, Carthik A. Sharma
BMCBI
2011
13 years 4 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
BMCBI
2011
13 years 4 months ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch
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