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BMCBI
2010
157views more  BMCBI 2010»
13 years 8 months ago
SeqTrim: a high-throughput pipeline for pre-processing any type of sequence read
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
Juan Falgueras, Antonio J. Lara, Noé Fern&a...
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
BMCBI
2008
141views more  BMCBI 2008»
13 years 8 months ago
EzArray: A web-based highly automated Affymetrix expression array data management and analysis system
Background: Though microarray experiments are very popular in life science research, managing and analyzing microarray data are still challenging tasks for many biologists. Most m...
Yuerong Zhu, Yuelin Zhu, Wei Xu
BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...
Joel Hedlund, Hans Jörnvall, Bengt Persson
BMCBI
2008
155views more  BMCBI 2008»
13 years 8 months ago
ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...
Kwangmin Choi, Sun Kim