Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
Federico Plazzi, Ronald R. Ferrucci, Marco Passamo...
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
Yaping Feng, Andrzej Kloczkowski, Robert L. Jernig...
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...