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IJKDB
2010
141views more  IJKDB 2010»
13 years 4 months ago
Mining Frequent Boolean Expressions: Application to Gene Expression and Regulatory Modeling
Regulatory network analysis and other bioinformatics tasks require the ability to induce and represent arbitrary boolean expressions from data sources. We introduce a novel framew...
Mohammed Javeed Zaki, Naren Ramakrishnan, Lizhuang...
ICIC
2009
Springer
13 years 5 months ago
Inference of Differential Equation Models by Multi Expression Programming for Gene Regulatory Networks
This paper presents an evolutionary method for identifying the gene regulatory network from the observed time series data of gene expression using a system of ordinary differential...
Bin Yang, Yuehui Chen, Qingfang Meng
BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2011
12 years 11 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli