57 search results - page 4 / 12 » Rich Parameterization Improves RNA Structure Prediction |
SAC
2009
ACM
14 years 2 months ago
2009
ACM
The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
WG
2005
Springer
14 years 27 days ago
2005
Springer
Abstract. In the context of protein engineering, we consider the problem of computing an mRNA sequence of maximal codon-wise similarity to a given mRNA (and consequently, to a give...
BMCBI
2008
13 years 7 months ago
2008
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
BMCBI
2011
13 years 1 months ago
2011
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
BMCBI
2006
13 years 7 months ago
2006
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...