Background: The identification of specific gene expression signature for distinguishing sample groups is a dominant field in cancer research. Although a number of tools have been ...
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Regularized kernel discriminant analysis (RKDA) performs linear discriminant analysis in the feature space via the kernel trick. Its performance depends on the selection of kernel...