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BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
13 years 7 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
CPM
2004
Springer
168views Combinatorics» more  CPM 2004»
14 years 1 months ago
The Protein Sequence Design Problem in Canonical Model on 2D and 3D Lattices
In this paper we investigate the protein sequence design (PSD) problem (also known as the inverse protein folding problem) under the Canonical model 4 on 2D and 3D lattices [12, 25...
Piotr Berman, Bhaskar DasGupta, Dhruv Mubayi, Robe...
JPDC
2007
167views more  JPDC 2007»
13 years 7 months ago
On the design of high-performance algorithms for aligning multiple protein sequences on mesh-based multiprocessor architectures
In this paper, we address the problem of multiple sequence alignment (MSA) for handling very large number of proteins sequences on mesh-based multiprocessor architectures. As the ...
Diana H. P. Low, Bharadwaj Veeravalli, David A. Ba...
IPPS
2006
IEEE
14 years 1 months ago
Parallelization and performance characterization of protein 3D structure prediction of Rosetta
The prediction of protein 3D structure has become a hot research area in the post-genome era, through which people can understand a protein’s function in health and disease, exp...
Wenlong Li, Tao Wang, Eric Li, D. Baker, Li Jin, S...
DNA
2005
Springer
14 years 1 months ago
Two Proteins for the Price of One: The Design of Maximally Compressed Coding Sequences
Abstract. The emerging field of synthetic biology moves beyond conventional genetic manipulation to construct novel life forms which do not originate in nature. We explore the pro...
Bei Wang, Dimitris Papamichail, Steffen Mueller, S...