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» SAT-based protein design
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BMCBI
2006
98views more  BMCBI 2006»
13 years 7 months ago
Optimised amino acid specific weighting factors for unbound protein docking
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
Philipp Heuser, Dietmar Schomburg
TCBB
2011
13 years 2 months ago
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
Zengyou He, Can Yang, Weichuan Yu
ICML
2008
IEEE
14 years 8 months ago
Sequence kernels for predicting protein essentiality
The problem of identifying the minimal gene set required to sustain life is of crucial importance in understanding cellular mechanisms and designing therapeutic drugs. This work d...
Cyril Allauzen, Mehryar Mohri, Ameet Talwalkar
BIRD
2008
Springer
13 years 9 months ago
Efficient Seeding Techniques for Protein Similarity Search
Abstract. We apply the concept of subset seeds proposed in [1] to similarity search in protein sequences. The main question studied is the design of efficient seed alphabets to con...
Mikhail A. Roytberg, Anna Gambin, Laurent No&eacut...
ISMB
1993
13 years 9 months ago
Protein Sequencing Experiment Planning Using Analogy
Experiment design and execution is a central activity in the natural sciences. The SeqERsystem provides a general architecture for the integration of automated planning techniques...
Brian P. Kettler, Lindley Darden