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BMCBI
2008
151views more  BMCBI 2008»
13 years 7 months ago
An integrated database-pipeline system for studying single nucleotide polymorphisms and diseases
Background: Studies on the relationship between disease and genetic variations such as single nucleotide polymorphisms (SNPs) are important. Genetic variations can cause disease b...
Jin Ok Yang, Sohyun Hwang, Jeongsu Oh, Jong Bhak, ...
BMCBI
2008
134views more  BMCBI 2008»
13 years 7 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
249views more  BMCBI 2006»
13 years 7 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
Towards a better solution to the shortest common supersequence problem: the deposition and reduction algorithm
Background: The problem of finding a Shortest Common Supersequence (SCS) of a set of sequences is an important problem with applications in many areas. It is a key problem in biol...
Kang Ning, Hon Wai Leong