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AB
2008
Springer
14 years 3 months ago
An Algorithm for Qualitative Simulation of Gene Regulatory Networks with Steep Sigmoidal Response Functions
A specific class of ODEs has been shown to be adequate to describe the essential features of the complex dynamics of Gene-Regulatory Networks (GRN). But, the effective exploitatio...
Liliana Ironi, Luigi Panzeri, Erik Plahte
TREC
2003
13 years 10 months ago
Identifying Gene Function Descriptions by Probability-based Sentence Selection
This paper proposes an approach to the secondary task in the TREC Genomics Track. We regard the task as identification of the sentences describing gene functions (i.e., GeneRIFs)...
Kazuhiro Seki, Nihar Sheth, Javed Mostafa
BMCBI
2005
127views more  BMCBI 2005»
13 years 8 months ago
Dynamic modeling of cis-regulatory circuits and gene expression prediction via cross-gene identification
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
ISBRA
2009
Springer
14 years 3 months ago
Using Gene Expression Modeling to Determine Biological Relevance of Putative Regulatory Networks
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Peter Larsen, Yang Dai
BMCBI
2006
123views more  BMCBI 2006»
13 years 9 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger