When using machine learning for in silico modeling, the goal is normally to obtain highly accurate predictive models. Often, however, models should also bring insights into intere...
Background: An important step in understanding the conditions that specify gene expression is the recognition of gene regulatory elements. Due to high diversity of different types...
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
A popular model for gene regulatory networks is the Boolean network model. In this paper, we propose an algorithm to perform an analysis of gene regulatory interactions using the B...
Carlos H. A. Higa, Vitor H. P. Louzada, Ronaldo Fu...
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...