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» SNAPper: gene order predicts gene function
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BMCBI
2005
100views more  BMCBI 2005»
13 years 8 months ago
Speeding disease gene discovery by sequence based candidate prioritization
Background: Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is...
Euan A. Adie, Richard R. Adams, Kathryn L. Evans, ...
GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
14 years 2 months ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...
HPCA
2006
IEEE
14 years 9 months ago
High performance file I/O for the Blue Gene/L supercomputer
Parallel I/O plays a crucial role for most data-intensive applications running on massively parallel systems like Blue Gene/L that provides the promise of delivering enormous comp...
Hao Yu, Ramendra K. Sahoo, C. Howson, G. Almasi, J...
NAR
2000
85views more  NAR 2000»
13 years 8 months ago
MitoNuc and MitoAln: two related databases of nuclear genes coding for mitochondrial proteins
Mitochondria, besides their central role in energy metabolism, have recently been found to be involved in a number of basic processes of cell life and to contribute to the pathoge...
Graziano Pesole, Carmela Gissi, Domenico Catalano,...
BMCBI
2010
131views more  BMCBI 2010»
13 years 6 months ago
A two-step site and mRNA-level model for predicting microRNA targets
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
Takaya Saito, Pål Sætrom