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BMCBI
2006
142views more  BMCBI 2006»
13 years 8 months ago
RDMAS: a web server for RNA deleterious mutation analysis
Background: The diverse functions of ncRNAs critically depend on their structures. Mutations in ncRNAs disrupting the structures of functional sites are expected to be deleterious...
Wenjie Shu, Xiaochen Bo, Rujia Liu, Dongsheng Zhao...
BMCBI
2004
140views more  BMCBI 2004»
13 years 8 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2006
130views more  BMCBI 2006»
13 years 8 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi
BMCBI
2004
135views more  BMCBI 2004»
13 years 8 months ago
Information assessment on predicting protein-protein interactions
Background: Identifying protein-protein interactions is fundamental for understanding the molecular machinery of the cell. Proteome-wide studies of protein-protein interactions ar...
Nan Lin, Baolin Wu, Ronald Jansen, Mark Gerstein, ...
ACIIDS
2010
IEEE
171views Database» more  ACIIDS 2010»
13 years 11 months ago
Evolving Concurrent Petri Net Models of Epistasis
Abstract. A genetic algorithm is used to learn a non-deterministic Petri netbased model of non-linear gene interactions, or statistical epistasis. Petri nets are computational mode...
Michael Mayo, Lorenzo Beretta