Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
Abstract. Contemporary high-end Terascale and Petascale systems are composed of hundreds of thousands of commodity multi-core processors interconnected with high-speed custom netwo...
Heike Jagode, Jack Dongarra, Sadaf R. Alam, Jeffre...
High-throughput, data-directed computational protocols for Structural Genomics (or Proteomics) are required in order to evaluate the protein products of genes for structure and fu...
The permutation procedure is widely used to assess the significance level (p-value) of a test statistic. This approach is asymptotically consistent. In genomics and proteomics st...