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» SUPFAM: A database of sequence superfamilies of protein doma...
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BMCBI
2006
159views more  BMCBI 2006»
13 years 7 months ago
EVEREST: automatic identification and classification of protein domains in all protein sequences
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
Elon Portugaly, Amir Harel, Nathan Linial, Michal ...
BMCBI
2008
178views more  BMCBI 2008»
13 years 7 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
NAR
2000
93views more  NAR 2000»
13 years 7 months ago
The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure,...
Amos Bairoch, Rolf Apweiler
BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
NAR
2007
124views more  NAR 2007»
13 years 7 months ago
EVEREST: a collection of evolutionary conserved protein domains
Protein domains are subunits of proteins that recur throughout the protein world. There are many definitions attempting to capture the essence of a protein domain, and several sys...
Elon Portugaly, Nathan Linial, Michal Linial