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BMCBI
2006
13 years 10 months ago
2006
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
BMCBI
2006
13 years 10 months ago
2006
Background: Many proteomics initiatives require integration of all information with uniformcriteria from collection of samples and data display to publication of experimental resu...
BMCBI
2006
13 years 10 months ago
2006
Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
BMCBI
2006
13 years 10 months ago
2006
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
BMCBI
2006
13 years 10 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...