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DAGM
2010
Springer
13 years 10 months ago
Gaussian Mixture Modeling with Gaussian Process Latent Variable Models
Density modeling is notoriously difficult for high dimensional data. One approach to the problem is to search for a lower dimensional manifold which captures the main characteristi...
Hannes Nickisch, Carl Edward Rasmussen
BMCBI
2010
143views more  BMCBI 2010»
13 years 9 months ago
An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location inf
Background: Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout al...
Kaname Kojima, Masao Nagasaki, Satoru Miyano
BMCBI
2010
137views more  BMCBI 2010»
13 years 9 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BMCBI
2010
117views more  BMCBI 2010»
13 years 9 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
BMCBI
2008
155views more  BMCBI 2008»
13 years 9 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang