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BMCBI
2010
205views more  BMCBI 2010»
13 years 7 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
COMPGEOM
2009
ACM
14 years 2 months ago
A general approach for cache-oblivious range reporting and approximate range counting
We present cache-oblivious solutions to two important variants of range searching: range reporting and approximate range counting. Our main contribution is a general approach for ...
Peyman Afshani, Chris H. Hamilton, Norbert Zeh
CIKM
2006
Springer
13 years 11 months ago
Structure-based querying of proteins using wavelets
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
Keith Marsolo, Srinivasan Parthasarathy, Kotagiri ...
BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...
RECOMB
2002
Springer
14 years 7 months ago
Revealing protein structures: a new method for mapping antibody epitopes
A recent idea for determining the three-dimensional structure of a protein uses antibody recognition of surface structure and random peptide libraries to map antibody epitope comb...
Brendan Mumey, Brian W. Bailey, Edward A. Dratz