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» Searching Without a Heuristic: Efficient Use of Abstraction
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EDBT
2010
ACM
152views Database» more  EDBT 2010»
13 years 11 months ago
Feedback-based annotation, selection and refinement of schema mappings for dataspaces
The specification of schema mappings has proved to be time and resource consuming, and has been recognized as a critical bottleneck to the large scale deployment of data integrati...
Khalid Belhajjame, Norman W. Paton, Suzanne M. Emb...
GECCO
2006
Springer
195views Optimization» more  GECCO 2006»
13 years 11 months ago
Studying XCS/BOA learning in Boolean functions: structure encoding and random Boolean functions
Recently, studies with the XCS classifier system on Boolean functions have shown that in certain types of functions simple crossover operators can lead to disruption and, conseque...
Martin V. Butz, Martin Pelikan
BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2008
155views more  BMCBI 2008»
13 years 7 months ago
AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
Tania Pencheva, David Lagorce, Ilza Pajeva, Bruno ...
BMCBI
2008
169views more  BMCBI 2008»
13 years 7 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...