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» Searching on the Secondary Structure of Protein Sequences
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BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
CORR
2006
Springer
159views Education» more  CORR 2006»
13 years 7 months ago
Structural Alignments of pseudo-knotted RNA-molecules in polynomial time
An RNA molecule is structured on several layers. The primary and most obvious structure is its sequence of bases, i.e. a word over the alphabet {A, C, G, U}. The higher structure i...
Michael Brinkmeier
ISMIS
2005
Springer
14 years 27 days ago
A Machine Text-Inspired Machine Learning Approach for Identification of Transmembrane Helix Boundaries
In this paper, we adapt a statistical learning approach, inspired by automated topic segmentation techniques in speech-recognized documents to the challenging protein segmentation ...
Betty Yee Man Cheng, Jaime G. Carbonell, Judith Kl...
BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
JCB
2006
215views more  JCB 2006»
13 years 7 months ago
Protein Fold Recognition Using Segmentation Conditional Random Fields (SCRFs)
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...