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TOMS
1998
148views more  TOMS 1998»
13 years 8 months ago
PELLPACK: A Problem-Solving Environment for PDE-Based Applications on Multicomputer Platforms
This paper presents the software architecture and implementation of the problem solving environment (PSE) PELLPACK for modeling physical objects described by partial differential ...
Elias N. Houstis, John R. Rice, Sanjiva Weerawaran...
BMCBI
2011
13 years 3 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
EDBT
2011
ACM
256views Database» more  EDBT 2011»
13 years 13 days ago
RanKloud: a scalable ranked query processing framework on hadoop
The popularity of batch-oriented cluster architectures like Hadoop is on the rise. These batch-based systems successfully achieve high degrees of scalability by carefully allocati...
K. Selçuk Candan, Parth Nagarkar, Mithila N...
SODA
2012
ACM
297views Algorithms» more  SODA 2012»
11 years 11 months ago
Constant factor approximation algorithm for the knapsack median problem
We give a constant factor approximation algorithm for the following generalization of the k-median problem. We are given a set of clients and facilities in a metric space. Each fa...
Amit Kumar
SPAA
2012
ACM
11 years 11 months ago
A scalable framework for heterogeneous GPU-based clusters
GPU-based heterogeneous clusters continue to draw attention from vendors and HPC users due to their high energy efficiency and much improved single-node computational performance...
Fengguang Song, Jack Dongarra