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BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
CSB
2002
IEEE
230views Bioinformatics» more  CSB 2002»
14 years 1 months ago
Prediction of Protein Function Using Protein-Protein Interaction Data
Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, ...
BIBM
2007
IEEE
135views Bioinformatics» more  BIBM 2007»
14 years 3 months ago
Graph Kernel-Based Learning for Gene Function Prediction from Gene Interaction Network
Prediction of gene functions is a major challenge to biologists in the post-genomic era. Interactions between genes and their products compose networks and can be used to infer ge...
Xin Li, Zhu Zhang, Hsinchun Chen, Jiexun Li
ICDM
2006
IEEE
127views Data Mining» more  ICDM 2006»
14 years 2 months ago
Predictive Integration of Gene Ontology-Driven Similarity and Functional Interactions
There is a need to develop methods to automatically incorporate prior knowledge to support the prediction and validation of novel functional associations. One such important sourc...
Francisco Azuaje, Haiying Wang, Huiru Zheng, Olivi...