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BMCBI
2010
94views more  BMCBI 2010»
13 years 7 months ago
A comparative study of conservation and variation scores
Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
Fredrik Johansson, Hiroyuki Toh
BMCBI
2005
132views more  BMCBI 2005»
13 years 7 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 1 months ago
TreeRefiner: A Tool for Refining a Multiple Alignment on a Phylogenetic Tree
We present TreeRefiner, a tool for refining multiple alignments of biological sequences. Given a multiple alignment, a phylogenetic tree, and scoring parameters as input, TreeRefi...
Aswath Manohar, Serafim Batzoglou
ARC
2007
Springer
123views Hardware» more  ARC 2007»
13 years 11 months ago
Multiple Sequence Alignment Using Reconfigurable Computing
The alignment of multiple protein (or DNA) sequences is a current problem in Bioinformatics. ClustalW is the most popular heuristic algorithm for multiple sequence alignment. Pairw...
Carlos R. Erig Lima, Heitor S. Lopes, Maiko R. Mor...
BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
Automatic detection of anchor points for multiple sequence alignment
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
Florian Pitschi, Claudine Devauchelle, Eduardo Cor...