Background: Conservation and variation scores are used when evaluating sites in a multiple sequence alignment, in order to identify residues critical for structure or function. A ...
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
We present TreeRefiner, a tool for refining multiple alignments of biological sequences. Given a multiple alignment, a phylogenetic tree, and scoring parameters as input, TreeRefi...
The alignment of multiple protein (or DNA) sequences is a current problem in Bioinformatics. ClustalW is the most popular heuristic algorithm for multiple sequence alignment. Pairw...
Carlos R. Erig Lima, Heitor S. Lopes, Maiko R. Mor...
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...