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BMCBI
2004
125views more  BMCBI 2004»
13 years 7 months ago
A fast algorithm for determining the best combination of local alignments to a query sequence
Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...
Gavin C. Conant, Andreas Wagner
IPPS
2008
IEEE
14 years 2 months ago
SWAMP: Smith-Waterman using associative massive parallelism
One of the most commonly used tools by computational biologists is some form of sequence alignment. Heuristic alignment algorithms developed for speed and their multiple results s...
Shannon Steinfadt, Johnnie W. Baker
CISIS
2010
IEEE
14 years 2 months ago
Scalability Analysis of Progressive Alignment on a Multicore
—Sequence alignment is a fundamental instrument in Bioinformatics. In recent years, numerous proposals have been addressing the problem of accelerating this class of applications...
Sebastian Isaza, Friman Sánchez, Georgi Gay...
GCB
2006
Springer
119views Biometrics» more  GCB 2006»
13 years 11 months ago
Comparative Analysis of Cyclic Sequences: Viroids and other Small Circular RNAs
: The analysis of small circular sequences requires specialized tools. While the differences between linear and circular sequences can be neglected in the case of long molecules su...
Axel Mosig, Ivo L. Hofacker, Peter F. Stadler
BMCBI
2006
148views more  BMCBI 2006»
13 years 7 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower