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CPM
2000
Springer
141views Combinatorics» more  CPM 2000»
14 years 1 months ago
A Lower Bound for the Breakpoint Phylogeny Problem
Breakpoint phylogenies methods have been shown to be an effective way to extract phylogenetic information from gene order data. Currently, the only practical breakpoint phylogeny a...
David Bryant
NIPS
2004
13 years 11 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
APVIS
2009
13 years 11 months ago
Visualization of signal transduction processes in the crowded environment of the cell
In this paper, we propose a stochastic simulation to model and analyze cellular signal transduction. The high number of objects in a simulation requires advanced visualization tec...
Martin Falk, Michael Klann, Matthias Reuss, Thomas...
BMCBI
2008
128views more  BMCBI 2008»
13 years 10 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...
BMCBI
2006
112views more  BMCBI 2006»
13 years 9 months ago
Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...