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BMCBI
2006
13 years 8 months ago
2006
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
BMCBI
2006
13 years 8 months ago
2006
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
BMCBI
2006
13 years 8 months ago
2006
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
BMCBI
2006
13 years 8 months ago
2006
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
BMCBI
2006
13 years 8 months ago
2006
Background: The goal of most microarray studies is either the identification of genes that are most differentially expressed or the creation of a good classification rule. The dis...