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ICSM
2007
IEEE
14 years 2 months ago
A Maintainable Software Architecture for Fast and Modular Bioinformatics Sequence Search
Bioinformaticists use the Basic Local Alignment Search Tool (BLAST) to characterize an unknown sequence by comparing it against a database of known sequences, thus detecting evolu...
Jeremy S. Archuleta, Eli Tilevich, Wu-chun Feng
CIKM
2005
Springer
14 years 1 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
ASPLOS
2004
ACM
14 years 1 months ago
FAB: building distributed enterprise disk arrays from commodity components
This paper describes the design, implementation, and evaluation of a Federated Array of Bricks (FAB), a distributed disk array that provides the reliability of traditional enterpr...
Yasushi Saito, Svend Frølund, Alistair C. V...
BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
14 years 1 months ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
CSB
2003
IEEE
121views Bioinformatics» more  CSB 2003»
14 years 1 months ago
Epitope Prediction Algorithms for Peptide based Vaccine Design
Peptide-based vaccines, in which small peptides derived from target proteins (epitopes) are used to provoke an immune reaction, have attracted considerable attention recently as a...
Liliana Florea, Bjarni V. Halldórsson, Oliv...