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» Semantics of Biological Regulatory Networks
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GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
13 years 11 months ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert
GECCO
2006
Springer
220views Optimization» more  GECCO 2006»
13 years 11 months ago
Comparing evolutionary algorithms on the problem of network inference
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different evoluti...
Christian Spieth, Rene Worzischek, Felix Streicher...
BMCBI
2010
240views more  BMCBI 2010»
13 years 7 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
BMCBI
2006
136views more  BMCBI 2006»
13 years 7 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara
ALIFE
2008
13 years 7 months ago
Exploring the Operational Characteristics of Inference Algorithms for Transcriptional Networks by Means of Synthetic Data
The development of structure-learning algorithms for gene regulatory networks depends heavily on the availability of synthetic data sets that contain both the original network and ...
Koenraad Van Leemput, Tim Van den Bulcke, Thomas D...