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BMCBI
2005
212views more  BMCBI 2005»
13 years 7 months ago
PAGE: Parametric Analysis of Gene Set Enrichment
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Seon-Young Kim, David J. Volsky
BMCBI
2005
122views more  BMCBI 2005»
13 years 7 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
BMCBI
2005
89views more  BMCBI 2005»
13 years 7 months ago
An empirical analysis of training protocols for probabilistic gene finders
Background: Generalized hidden Markov models (GHMMs) appear to be approaching acceptance as a de facto standard for state-of-the-art ab initio gene finding, as evidenced by the re...
William H. Majoros, Steven Salzberg
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Computational identification of strain-, species- and genus-specific proteins
Background: The identification of unique proteins at different taxonomic levels has both scientific and practical value. Strain-, species- and genus-specific proteins can provide ...
Raja Mazumder, Darren A. Natale, Sudhir Murthy, Ra...
BMCBI
2005
147views more  BMCBI 2005»
13 years 7 months ago
GATA: a graphic alignment tool for comparative sequence analysis
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
David A. Nix, Michael B. Eisen
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