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» Sequence Comparison Using a Relational Database Approach
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BMCBI
2005
125views more  BMCBI 2005»
13 years 7 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
SISAP
2008
IEEE
166views Data Mining» more  SISAP 2008»
14 years 2 months ago
Approximate Similarity Search in Genomic Sequence Databases Using Landmark-Guided Embedding
Similarity search in sequence databases is of paramount importance in bioinformatics research. As the size of the genomic databases increases, similarity search of proteins in the...
Ahmet Sacan, Ismail Hakki Toroslu
IPPS
2003
IEEE
14 years 28 days ago
Using Hybrid Alignment for Iterative Sequence Database Searches
Progressive sequence model refinement by means of iterative searches is an effective technique for high sensitivity database searches and is currently employed in popular tools s...
Yuheng Li, Mario Lauria, Ralf Bundschuh
BMCBI
2008
152views more  BMCBI 2008»
13 years 7 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...
BMCBI
2004
150views more  BMCBI 2004»
13 years 7 months ago
SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Chunlin Wang, Elliot J. Lefkowitz