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» Sequence Complexity for Biological Sequence Analysis
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CIBCB
2005
IEEE
14 years 2 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
BMCBI
2010
153views more  BMCBI 2010»
13 years 9 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2006
127views more  BMCBI 2006»
13 years 9 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
RECOMB
2008
Springer
14 years 9 months ago
Sorting Cancer Karyotypes by Elementary Operations
Since the discovery of the "Philadelphia chromosome" in chronic myelogenous leukemia in 1960, there is an ongoing intensive research of chromosomal aberrations in cancer....
Michal Ozery-Flato, Ron Shamir
BMCBI
2005
108views more  BMCBI 2005»
13 years 9 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...