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» Sequence Complexity for Biological Sequence Analysis
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BMCBI
2006
138views more  BMCBI 2006»
13 years 7 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...
BMCBI
2006
114views more  BMCBI 2006»
13 years 7 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...
WABI
2010
Springer
128views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Sparsification of RNA Structure Prediction Including Pseudoknots
Background: Although many RNA molecules contain pseudoknots, computational prediction of pseudoknotted RNA structure is still in its infancy due to high running time and space con...
Mathias Möhl, Raheleh Salari, Sebastian Will,...
BMVC
2010
13 years 5 months ago
Iterative Hyperplane Merging: A Framework for Manifold Learning
We present a framework for the reduction of dimensionality of a data set via manifold learning. Using the building blocks of local hyperplanes we show how a global manifold can be...
Harry Strange, Reyer Zwiggelaar
BMCBI
2011
13 years 2 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein